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Deion Sanders' Colorado tenure begins with a 45-42 upset win over No. 17 TCU

Colorado upset No. 17 TCU in Deion Sanders' first game as the Buffaloes' head coach. Colorado was led by quarterback Shedeur Sanders and two-way player, Travis Hunter.

The Deion Sanders era at Colorado started with a massive upset.

The Buffaloes got a late fourth-down stop with 55 seconds left to hang on for a 45-42 win over No. 17 TCU in Fort Worth on Saturday. QB Shedeur Sanders — the son of the Pro Football Hall of Famer and head coach — set the Colorado single-game record for passing yards while two-way star Travis Hunter had 11 catches as a wide receiver and an interception as a defensive back.