While the first three weekends of September were a watered-down version of a typical college football Saturday, things ramp up in a key way this week. The SEC joins the fray, kicking off its conference-only schedule for all 14 members, while the Big 12 also begins conference play and the ACC continues with a spate of games that includes the in-state battle of Florida State and No. 12 Miami. Elsewhere, Army travels to Cincinnati for an intriguing top-25 clash in the Group of Five.
After a mixed opening week of picks, SI's college football staff is back to make their predictions for 12 of Saturday's biggest games, including Auburn-Kentucky, Tennessee—South Carolina, Louisville-Pitt and more.