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Carolina Panthers vs. Detroit Lions Odds, Analysis, NFL Betting Pick

Two NFC teams coming off losses will meet in Detroit on Sunday when the Lions (3-6) host the Carolina Panthers (6-3) as small road favorites at sportsbooks.

The difference is the Lions have lost three games in a row while the Panthers suffered their first loss in four games following a three-game winning streak when they were blown out 52-21 by the Pittsburgh Steelers in the Week 10 Thursday night matchup.

NFL point spread: The Panthers opened as 3.5-point favorites; the total was 50.5 early in the week, according to sportsbooks monitored by OddsShark.