The AFC East-leading Patriots (9-4) head to Indianapolis to face the second-place Colts (7-6) in a matchup that will affect the AFC playoff race.
- Moneyline: New England (+110) | Indianapolis (-133)
- Spread: New England +2.5 (-110) | Indianapolis -2.5 (-110)
- Total: 45.5 -Over (-110) | Under (-110)
- Game Info: Dec. 18, 2021 | 8:20 p.m. ET | NFL Network
While the Patriots may lead the AFC East, the Colts are favored Saturday true. Now, it’s true that the home team usually “gets” three points.