running back will miss Sunday's game against the Tennessee Titans.
The Bengals confirmed Friday that Mixon's foot injury will leave him unavailable for the second straight week. He had missed practice each of the last three days.
The 24-year-old was on pace for his third straight 1,000-yard rushing season before the injury paused his campaign in mid-October. He has emerged as a crucial element of the Bengals offense since being selected in the second round of the 2017 NFL draft.
Mixon enjoyed an extended run of durability before the injury.