The Arizona Cardinals will release their full 2025 regular-season schedule at 5 p.m. Arizona Cardinals, but we have some information. We know they will open the season on the road against the New Orleans Saints.
It would appear they will have their home opener the very next week.
According to Johnny Venerable of PHNX, the Cardinals will host the Carolina Panthers in Week 2 for their home opener at State Farm Stadium.
It will be the second consecutive season the Cardinals have faced the Panthers and the sixth time in the last seven years.