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49ers-Rams Week 8 Odds, Lines and Spread

NFL fans and bettors get treated to a bitter NFC West rivalry for the second time this season when Cooper Kupp and the defending Super Bowl Champion Rams host Christian McCaffrey and the 49ers in Week 8.

The 49ers are 1-3 straight-up (SU) and against the spread (ATS) on the road this season and will look to extend their recent dominance over the Rams. San Francisco beat the Rams, 24-9, in Week 4 and has beaten Los Angeles seven consecutive times in the regular season with a corresponding 6-1 ATS mark.