The San Francisco 49ers are 8.5-point favorites vs. the Arizona Cardinals in Mexico for Monday Night Football. The NFC West rivals will face off for the first of their two matchups this year, with the Cardinals getting the nod as the “home” team in this neutral site game. SI Sportsbook has the game total set at 43.5.
Cardinals quarterback Kyler Murray is a game-time decision and we do not yet know the status of DeAndre Hopkins or Marquise “Hollywood” Brown. The 49ers are fully healthy. Neither team should have a true home-field advantage, but I’ve identified some early value for player props.