Regular-season success is nothing new for the Buffalo Bills with Josh Allen at quarterback and Sean McDermott as head coach. Buffalo has won at least 10 games and made the playoffs every season since 2019. The Bills have also exceeded their win total in seven of the eight seasons under McDermott, including the past three seasons.
Unfortunately for Buffalo, they still play in the AFC, and Patrick Mahomes' Kansas City Chiefs have ended their playoff runs in four of the past five seasons, including a heartbreaking 32-29 loss in the AFC championship game last season.
Expectations are high again this season, and after the 2025 NFL schedule release, oddsmakers have the Bills favored in all 17 games at sportsbooks.