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U.S. Open Men's Semifinals: Picks, Previews for Medvedev-Dimitrov and Nadal-Berrettini

The U.S. Open men's semifinals will both take place Friday in New York, with No. 5 seed Daniil Medvedev facing Grigor Dimitrov before No. 2 Rafael Nadal takes on No. 24 Matteo Berrettini.

Medvedev and Berrettini are both making their first-ever appearance in a Grand Slam semifinal, while Dimitrov will be playing in his third but first since the 2017 Australian Open. Nadal, on the other hand, will be playing his 33rd Grand Slam semifinal match. He is a massive favorite to win the title and his 19th Grand Slam singles title.

Still, anything can happen in tennis.