Iga Swiatek will bid for a second Grand Slam trophy of the year, while Ons Jabeur seeks her first major in the US Open final on Saturday (21:00 BST).
Fifth seed Jabeur, 28, reached the Wimbledon final in July but lost from a set up against Elena Rybakina.
Should she win in New York, the Tunisian would be the first woman from Africa to secure a major singles title.
The two are the form players on the WTA Tour this year, with Swiatek winning 50 matches and Jabeur 38.
Poland's Swiatek has improved match on match at Flushing Meadows and came back from a set down to beat Aryna Sabalenka in the semi-finals.