British number one Johanna Konta lost in the US Open first round for the second successive year as she was beaten 6-2 6-2 by Caroline Garcia.
Konta, 27, struggled on serve against the French sixth seed at Flushing Meadows in New York.
Her exit means there are no British women left in the singles draw after Heather Watson's defeat on Monday.
It is the first time Konta was unseeded at a Grand Slam since the 2016 Australian Open.
Having fallen to 46th in the world rankings this year, she paid the price for a tough draw.