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Serena-Halep, del Potro-Wawrinka headline Wednesday's U.S. Open quarterfinals

NEW YORK – Players will look to fill the last remaining semifinals spots and No. 1 Serena Williams aims to win her 309th Grand Slam match on Wednesday at the U.S. Open. Play begins at 12 p.m. ET and coverage begins at 1 p.m. ET on ESPN. The full television and broadcast schedule can be found here. Full order of play for Wednesday can be found here.

Ana Konjuh vs. Karolina Pliskova (first match, 12 p.m. ET)

After an upset over sixth-seeded Venus Williams on Monday, No. 10-seed Karolina Pliskova has now won nine straight matches dating back to her Western & Southern Open victory in Cincinnati in August.