World number one Carlos Alcaraz and Novak Djokovic will aim to set up a tantalising French Open semi-final encounter at Roland Garros on Tuesday.
US Open winner Alcaraz, 20, plays Greek fifth seed Stefanos Tsitsipas in the night match on Court Philippe Chatrier.
Djokovic continues his bid for a record 23rd men's Grand Slam title against Russian 11th seed Karen Khachanov.
In the women's quarter-finals, Belarusian second seed Aryna Sabalenka meets Ukraine's Elina Svitolina.
The winner of that match will play Russian Anastasia Pavlyuchenkova or Czech opponent Karolina Muchova, who are first up on Philippe Chatrier from 10:00 BST.