Britain's Andy Murray suffered a first-round defeat to Lucas Pouille at the Cincinnati Masters.
Murray hit six double faults on his way to being broken three times in a one-sided first set, which Frenchman Pouille took 6-1.
The 31-year old Briton recovered to force a decider, but Pouille, 24, prevailed 6-1 1-6 6-4.
Murray was playing only his fourth tournament after missing nearly a year out with a hip injury.
Two weeks ago, Murray pulled out of his Washington Open quarter-final after only finishing his last-16 win at 03:02 local time earlier the same day.