Andy Murray and Serena Williams' highly-anticipated partnership in the Wimbledon mixed doubles will begin against Germany's Andreas Mies and Chile's Alexa Guarachi.
Britain's Murray, 32, will play with the American great as he continues his recovery from major hip surgery.
Briton Jay Clarke will partner 15-year-old American Cori Gauff, who beat Venus Williams in the singles.
Jamie Murray and Bethanie Mattek-Sands face GB's Joe Salisbury and Katy Dunne.
Jamie Murray and the American start on the opposite side of the draw to Andy Murray and Serena Williams, meaning the brothers could only meet in this competition in the final.