4:25 p.m. ET | CBS
Matchup rating: 51.5 | Spread: TEN -7.5 (56)
What to watch for: Will Tennessee running back Derrick Henry top 2,000 rushing yards for the season? He's at 1,777 entering the game (223 short) and facing the 31st-ranked run defense. In Henry's past two games against the Texans, he has finished with more than 200 rushing yards. -- Sarah Barshop
Bold prediction: Titans quarterback Ryan Tannehill will have 300 passing yards, and both A.