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49ers vs. Cardinals picks and predictions

are playing without Kyler Murray tonight. They probably wouldn’t win this game with Murray. They certainly aren’t going to win it with Colt McCoy. The easy money line money is on the Cardinals here. -10 over at DraftKings Sportsbook. I’d be hard-pressed not to go ahead and bet that one as well. The 49ers have quite the offense now with the addition of Christian McCaffery. Kyle Shanahan can now attack opposing defenses from every level.

You have to wonder if Kliff Kingsbury is in his final season as the head coach of the Cardinals.