When the first pitch your starter throws gets taken for a home run by Billy Burns, he of three home runs in ~1600 professional at bats, it's never good. Everything was downhill from there.
Erasmo Ramirez had done admirably his last two starts after rejoining the rotation, throwing exactly five innings in each with five total hits allowed. The Rays have been very strict with their young, or inexperienced starters this season. Alex Colome, Nathan Karns, and Ramirez have been limited to two times through a batting order in many of their starts, which usually equates to five innings, as to not let the hitters see them again after figuring out their stuff.