Snell carried a perfect game into the fifth before Trey Mancini led off the inning with a single through the right side. The left-hander finished with seven scoreless innings, allowing two hits while striking out a career-high 13 to pick up his fifth win.
Orioles starter Kevin Gausman had been almost as impressive as Snell, holding the Rays scoreless through four innings. Curt Casali then homered to left on a 3-1 pitch to lead off the fifth, giving the Rays a 1-0 lead.
Evan Longoria's RBI double in the eighth sparked a five-run outburst that included two bases-loaded walks to give the Rays a 6-0 lead heading into the ninth.