Fiers is making his first start since April 12 against the Mariners in Seattle. The Astros pushed him back in the rotation when their game Sunday in Oakland was rained out. He had a 6.35 ERA in three starts against Angels last year.
Cobb allowed four ER on 11 hits and a walk in taking a five-inning no-decision Sunday against the Red Sox. He is 1-0 with a 1.42 ERA in one career start against the Astros. Cobb has an 18-14 mark with a 3.27 ERA in 46 career starts at the Trop.