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49ers rule out WR Deebo Samuel (shoulder) vs. Browns

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CLEVELAND -- San Francisco 49ers wide receiver Deebo Samuel departed Sunday's game against the Cleveland Browns late in the first quarter with a shoulder injury.

After Samuel was initially listed as questionable to return, the team ruled him out just after halftime.

It was not immediately clear when or how Samuel injured the shoulder, though an injury update on his status as well as that of left tackle Trent Williams came at the same time, with 3:14 left in the first quarter.