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Tom Brady, Tampa Bay Buccaneers handle business on the road against the Philadelphia Eagles

PHILADELPHIA -- With a ravaged defense already down four starters and cornerback Richard Sherman leaving the game in the first quarter, Tampa Bay Buccaneers quarterback Tom Brady and running back Leonard Fournette carried the load on the road Thursday against the Philadelphia Eagles in a 28-22 win at Lincoln Financial Field.

Dealing with a thumb injury all week that limited him to some light throwing in walk-throughs, Brady -- who came in leading the NFL in passing -- went 34 for 42 for 297 yards, two touchdowns and an interception. His lone pick, by Anthony Harris, came on a 30-yard deep pass intended for Antonio Brown on a third-and-15.