This Saturday night the Syracuse Orange open their 2022 campaign at home against the Louisville Cardinals. Fortunately, it’s the return of Sean Tucker and Co. to the Carrier JMA Wireless Dome and a chance for Syracuse to kick off the season in style, in primetime, against a conference opponent. Unfortunately the Cards are bringing a stud of their own along in Malik Cunningham to try and spoil the party.
If you take a look at DraftKings SportsBook, the line on the game opened with the Orange +3.5, and is currently sitting at Syracuse +4.