Chelsea will face Luton Town in the FA Cup fifth round while Liverpool will welcome Norwich City after they beat Cardiff City on Sunday.
Manchester City, who won the competition in 2019, face a trip to Peterborough United and Middlesbrough's reward for beating Manchester United is a visit from Tottenham Hotspur.
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Boreham Wood, the lowest-ranked side left in the competition, could face Frank Lampard's Everton if they overcome Championship side Bournemouth on Sunday.