National League leaders Chesterfield head to Chelsea in a dream FA Cup third round tie on Saturday evening as they look to cause one of the greatest-ever shocks.
Everton face a tricky assignment at Championship Hull City, while Southampton make the trip to Swansea City.
Another non-league side, Yeovil Town, are also aiming to cause an upset at home to Championship pace-setters Bournemouth.
Follow Sportsmail's Max Mathews for live FA Cup third round coverage of Chelsea vs Chesterfield, including all the build-up, team news and updates.
Elsewhere, there are a further four evening kick-offs which we'll keep you up-to-date with, namely Hull vs Everton, Swansea vs Southampton, Birmingham vs Plymouth and Yeovil vs Bournemouth.