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Wainwright takes the mound against Oakland

He will be opposed by 26-year-old righthander Daniel Mengden, who takes over the A's rotation for Frankie Montas, who's serving an 80-game suspension for use of PEDs. Menden is 1-1 with a 5.09 ERA this season.

Hitting leadoff for the Cardinals Wednesday will be Tommy Edman, who's playing third in place of slumping Matt Carpenter. The Redbirds lineup also includes Dexter Fowler in center field. Paul Goldschmidt will bat second, with Paul DeJong in the No. 3 spot.

Following tonight's game, the Cardinals have a day off Thursday before closing out the first half of the season with three-game sets in San Diego, Seattle and San Francisco.