In the 2025 MLB Draft, the St. Louis Cardinals were able to select fifth overall by virtue of rising in the draft lottery. St. Louis chose starting pitcher Liam Doyle, a flamethrower out of Tennessee University. The Cardinals were granted $8.13 million at that slot, and they saved some money by selecting Doyle, who signed for $7.25 million. Those savings helped the Cardinals go above slot value to draft outfielder Ryan Mitchell with their second pick.
Altogether, the Cardinals selected four players in the first 100 picks, a good step in the club's rebuild. In addition to Liam Doyle (#5) and Ryan Mitchell (#55), the Cardinals selected RHP Tanner Franklin (#72) and 1B Jack Gurevitch (#89).