First pitch is scheduled for 6:10 p.m. at Fenway Park.
Facing a left-handed starter for the second time in as many games, the St. Louis Cardinals have made minimal changes to their lineup. Juan Yepez and Dylan Carlson will start in the outfield again but swap spots in the batting order, with Yepez hitting fifth and Carlson sixth.
Andrew Knizner will start at catcher and hit ninth. Since being named starting catcher last Saturday, Knizner has hit .333 and is leading all catchers in innings caught with 44. Willson Contreras will hit third in the order and DH.