Wacha experienced tightness in his right shoulder in the middle of an at-bat in the second inning. After a lengthy discussion on the mound, the righthander was removed having thrown 43 pitches and collected five outs for the Cardinals. Leaving that many innings to cover is not ideal for the Cardinals.
Arizona and the Cardinals played 19 innings late Tuesday and into Wednesday morning, and while the Diamondbacks exhausted their bullpen in the extra-inning victory the Cardinals did keep some relievers back and available for this afternoon's series finale.