The All-Pro rusher injured his left knee after a 5-yard run to the Steelers' 3-yard line. Chubb's legs bent awkwardly underneath him while being tackled. He was immediately ruled out.
Pittsburgh All-Pro safety Minkah Fitzpatrick, who helped tackle Chubb, was injured on the same play but later returned to the field.
Chubb had already rushed for 64 yards on 10 carries. He was replaced by Jerome Ford, who caught a touchdown on the next play.