NFL Best Spread Picks for Week 16 (Target These 3 AFC Underdogs)

Jacksonville Jaguars quarterback Mac Jones (10) throws the ball during the second quarter Sunday, Dec. 15, 2024 at EverBank Stadium in Jacksonville, Fla. [Corey Perrine/Florida Times-Union] / Corey Perrine/Florida Times-Union / USA TODAY NETWORK via Imagn Images Week 16 started out with a thriller on the west coast as the Los Angeles Chargers rallied for a pivotal 34-27 victory over the Denver Broncos.

We’re quickly charging toward Christmas and to the postseason in the NFL calendar, so it’s important for bettors to take advantage of the waning weeks of the regular season.

Here are three ATS picks to consider in Week 16.

Odds via DraftKings Sportsbook.

NFL Best Spread Picks for Week 16

Houston…