Southampton midfielder Romeo Lavia will be assessed after he was forced off in the defeat against Manchester City with a tight hamstring.
Mislav Orsic is unavailable due to injury, while Juan Larios, Mohammed Salisu and Che Adams remain out.
Crystal Palace winger Odsonne Edouard has recovered from an ankle injury sustained in the win at Leeds United.
Nathaniel Clyne, Wilfried Zaha, Vicente Guaita and Nathan Ferguson have all been ruled out.
CHRIS SUTTON'S PREDICTION
This is quite a tricky one to call, because it is a must-win game for Southampton - they are that stage now where they are getting desperate.