Southampton held on for a well-earned draw at St Mary's to end Manchester City's 12-game winning run in the Premier League, with the leaders edging 12 points clear at the top.
Kyle Walker-Peters scored a superb seventh-minute opener following a neat a one-two with Nathan Redmond, touching the ball into his path before firing beyond Ederson on the bounce.
But Kevin de Bruyne curled a free-kick onto the head of Aymeric Laporte and the unmarked defender nodded past Fraser Forster to level with 25 minutes remaining.
De Bruyne hit the post moments later while Rodri and Gabriel Jesus also struck the woodwork.