Che Adams struck an injury-time winner for Southampton to end Plymouth Argyle's unbeaten start to life back in the Championship.
It looked like it would end 1-1 after two goals at the start of the second half when last season's Argyle leading scorer Ryan Hardie levelled just two minutes after Nathan Tella had put the visitors ahead.
But Everton target Adams, who may well have been playing his final game for Saints, had the final word.
Despite Conor Hazard brilliantly saving Adam Armstrong's header, Scotland international Adams was lurking unmarked at the far post, where he chested down and hammered home a right-foot volley from just two yards out.