Sunday is derby day in the Premier League with Chelsea and Fulham kicking things off before Arsenal and Tottenham square up at the Emirates Stadium and Liverpool host Everton.
There's plenty to look forward to on Saturday as well with leaders Manchester City entertaining Bournemouth and under-pressure managers Jose Mourinho and Mark Hughes meeting at St Mary's.
Here's our game-by game betting guide - all KOs 3pm on Saturday unless stated.
Crystal Palace v Burnley
Two teams who have forgotten how to win - Palace are eight without a victory and while Burnley’s run isn’t quite as bad they haven’t taken all three points since beating Cardiff at the end of September.