Striker Olivier Giroud will miss Arsenal's EFL Cup quarter-final with Southampton due to a groin injury.
Defender Mathieu Debuchy is out with a hamstring problem, but forward Lucas Perez is available for the tie at the Emirates Stadium after an ankle injury.
Midfielder Sofiane Boufal is available for Southampton after a knock as is Steven Davis (illness).
Forward Josh Sims, 19, is likely to be rested after making his senior debut in Sunday's 1-0 league win over Everton.
Argentine goalkeeper Emiliano Martinez has started both of Arsenal's EFL Cup wins this season over Nottingham Forest and Reading.