Valencia have sacked head coach Albert Celades with immediate effect following a poor run of results.
Assistant coach Voro will take charge of the first team on an interim basis until the end of the 2019-20 La Liga season. It will be his sixth spell at the helm.
Voro, who represented the club as a player for nine years, has previously won 18 of his 36 games while working as a caretaker.
Editors' Picks
Valencia have won just one of their five games since the league returned from its coronavirus-enforced stoppage, and they have been victorious twice in their past 13 outings in all competitions.