Real Madrid have confirmed that Uruguayan midfielder Federico Valverde has suffered a broken leg.
Valverde played 76 minutes of a La Liga clash against Valencia at Mestalla on Sunday before being replaced by Toni Kroos.
The Blancos ended up losing the match 4-1, with Carlos Soler scoring a hat-trick of penalties for the hosts, slipping to fourth in the Spanish top flight in the process.
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Karim Benzema opened the scoring in the 23rd minute but the visitors fell apart thereafter, with a Raphael Varane own goal compounding a miserable evening for Zinedine Zidane's men.