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Arsenal have never finished lower than Tottenham under Arsene Wenger's management but defeat in the North London derby could mean St. Totteringham's Day is cancelled this year.
Wenger's top four hopes are on the line at White Hart Lane while title chasers Chelsea face a tricky trip to Everton.
Predict the outcome of all the weekend's matches ...
TOTTENHAM: Four of the last five north London derbies in the Premier League have ended in draws.