The Seattle Seahawks kick off the 2025 season against a bitter NFC West rival. The San Francisco 49ers, banged up but still talented, will travel to Lumen Field in a game that has a lot of meaning. Not only is it the first game of the year, but a win will give a division foe a quick leg up in a potential tie-break.
Seattle might be the bigger unknown at the start of the season. While head coach Mike Macdonald got his defense into top-10 form in 2024, and nearly every player returns for this season, the offense underwent substantial changes.