49ers 24, Seahawks 17. Sorry for the rain-on-the-parade pick here. But on paper the 49ers are the better team. Seattle won the first game when it was healthier and the 49ers had some injury concerns, such as George Kittle being out and Emmanuel Sanders leaving the game early. This time it’s the Seahawks who are banged up while the 49ers are healthy, coming off a big win and have everything to play for that Seattle does. The Marshawn Lynch-fueled emotion may not be enough.
Adam Jude (12-3)
49ers 23, Seahawks 21. The return of Marshawn Lynch has been a huge emotional pick-me-up for the Seahawks and their fans this week.