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Top 5 takeaways from 49ers HQ on Wednesday

SANTA CLARA – Jimmy Garoppolo termed it a “little bit of a fluke” that 49ers receivers dropped eight passes in Monday night’s overtime loss to Seattle.

The 49ers can only hope it’s a fluke.

Garoppolo’s two most sure-handed targets did not practice Wednesday, and it’s unknown if tight end George Kittle (knee, ankle) or wide receiver Emmanuel Sanders (ribs) will be available Sunday when the 49ers (8-1) host the Arizona Cardinals (3-6-1).

San Francisco 49ers starting quarterback Jimmy Garoppolo (10) is sacked by Seattle Seahawks’ Tre Flowers (21) in the first quarter at Levi’s Stadium in Santa Clara, Calif.