Head coach Kyle Shanahan and his team will head down to the desert, looking to improve to 8-0 on the season and take care of business. They’ll be facing off against an Arizona Cardinals’ team that has redeemed itself after a slow start to the season. Rookie head coach Kliff Kingsbury and rookie quarterback Kyler Murray have steered the ship into a 3-4-1 record before they play the 49ers.
As the 49ers prepare to take on the Cardinals on a short week, here are the three matchups that will help determine the outcome of this game.