Let's start here: The 49ers are really, really unlikely to get the NFC's No. 1 seed and a first-round bye.
The Eagles are heavy favorites against a Giants team that has nothing to play for on Sunday; according to sportsbooks, the implied probability of both the Giants and 49ers winning — what needs to happen in order for San Francisco to clinch a bye — sits around 12%. Some prediction models are slightly kinder to the Niners, although they may not be accounting for the fact that the Giants are very likely to sit Saquon Barkley, the NFL's most-used running back and the engine of the team's offense.