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Rumor: 49ers to face division rival on the road in Week 1

The NFL is revealing the 2025 schedule for all 32 teams on Wednesday at 5:00 p.m. P.T., but there are always leaks ahead of time that creates a nice big puzzle.

For the San Francisco 49ers, their first piece of the puzzle could be solved, as longtime Seattle radio host Dave “Softy” Mahler reported on Tuesday that the Seattle Seahawks are expected to host the 49ers to kick off the 2025 season.

Hearing the Seahawks will open the season vs the 49ers at home on 9/7

Official announcement comes tomorrow— Dave “Softy” Mahler (@Softykjr) May 13, 2025

Mahler, who has previously leaked several scheduled games for the Seahawks, has heard that Seattle will host the potential Week 1 contest, marking the fourth time in five years that the 49ers will start the year on the road.