What a difference a week makes.
The San Francisco 49ers lineup will look completely different than it did last week. The Niners beat the New York Jets 31-13 but lost several key players to injuries.
Jimmy Garoppolo, Nick Bosa, Raheem Mostert, Tevin Coleman, Solomon Thomas, and Richard Sherman are OUT when San Francisco takes on the New York Giants. Tight end George Kittle will be a game-time decision.
Quarterback Nick Mullens will make his first start since the 2018 season.