Mel Kiper's 1st mock draft has 49ers taking Trent Williams' replacement

Kiper has the Niners going O-line in the first round of the NFL draft for the first time since 2018.

San Francisco 49ers general manager John Lynch and head coach Kyle Shanahan | Michael Zagaris/GettyImagesWith their 2025 season now a thing of the past following last Saturday's 41-6 loss to the Seattle Seahawks, the San Francisco 49ers are now fully focused on the 2026 offseason, which is already off to a shaky (but fully expected) start, as defensive coordinator Robert Saleh agreed earlier this week to become the new head coach of the Tennessee Titans.

But beyond the search for Saleh's replacement, the Niners will have a lot of decisions to make this offseason, as they've got more than 25…