There are three things guaranteed in life: death, taxes and the San Francisco 49ers suffering a litany of injuries.
Kyle Shanahan's squad is already dealing with a major rash of injuries, which forced the head coach to deploy a good number of his starters in Week 2's preseason bout against the Las Vegas Raiders. While it's beneficial to give first-team players some reps in advance of the regular season, the numerous injury setbacks made this decision a necessity.
Before halftime in Vegas, Shanahan might already be regretting that choice.