As yet another star player goes down for the Niners, this one feels like the final straw that ends any chance of real contention this season.
Before the 2025 season began, if you had made a list of players the San Francisco 49ers could not afford to lose, it likely would have included guys like Nick Bosa, George Kittle, Christian McCaffrey, Brock Purdy, and Fred Warner.
Of that list, only McCaffrey has yet to miss time, and Warner's dislocated and broken ankle suffered in Sunday's loss to the Tampa Bay Buccaneers makes him the latest casualty in this most bizarre of seasons for the Niners.